Renal Histologic Parameters Influencing Postoperative Renal Function in Renal Cell Carcinoma Patients

Renal Histologic Parameters Influencing Postoperative Renal Function in Renal Cell Carcinoma Patients

BACKGROUND Pre-existing non-neoplastic renal diseases or lesions may influence patient renal function after tumor removal. However, its description is often neglected or omitted in pathologic reports. To determine the incidence and clinical significance of non-neoplastic lesions, we retrospectively examined renal tissues obtained during 85 radical nephrectomies for renal cell carcinoma. METHO...

Sarcomatoid Transrormation of Chromophobe Renal Cell Carcinoma

Factors influencing prognosis in renal cell carcinoma.

Introduction Renal cell carcinoma (RCC) is unique in many aspects, Firstly, its response to chemotherapy, radiotherapy and hormonal manipulation is extremely poor leaving surgical extirpation as only effective means of treatment. Secondly, sometimes secondaries regress after removal of the primary tumor indicating unusual response to host defense system once tumor burden is reduced. RCC’s unpre...

Prognostic value of p53 in renal cell carcinoma

Background and Objectives: RCC is one of the most common genitourinary cancers. Accurate prediction of prognosis would be valuable for adjuvant trial design, counseling and effectively scheduling follow up visits. P53 is a tumor suppressor gene that expresses a protein that involved in both cell-cycle ar...

Sarcomatoid Chromophobe Renal Cell Carcinoma with Heterologous Component

Clear cellrenal cell carcinoma (RCC) is the most common malignant renal tumor in adults, while chromophobe RCC (CRCC) is the third most common. Any subtypes of RCC can undergo sarcomatoid differentiation, but heterologous differentiation in sarcomatoid area is very rare in RCC. Here a61-year male is presented with hematuria and palpable mass. Clinicoradiologically, RCC was considered and left r...